What are the sensitivity and the specificity of specific IgE testing in the diagnosis of validated cases of occupational asthma?
|
**
|
2+
|
Both skin prick and serological tests are sensitive for detecting specific IgE and occupational asthma caused by acid anhydrides and some reactive dyes; but have a lower specificity for diagnosing asthma.
|
This statement is in the "Diagnosis of an affected worker"
section of evidence linked statements
Evidence
Grammer L, Shaughnessy M, Kenamore B
,
Utility of antibody in identifying individuals who have or will develop anhydride-induced respiratory disease
,
Chest
,
1998
;
114
:
1199-1202
Howe W, Topping MD, Hawkins R, Newman Taylor AJ
,
Tetrachlorophthalic anhydride asthma: evidence for specific IgE antibody
,
J Allergy Clin Immunol
,
1983
;
71
:
5-11
Park HS, Kim YJ, Lee MK et al
,
Occupational asthma and IgE antibodies to reactive dyes
,
Yonsei Med J
,
1989
;
30
:
298-304
Park JW, Kim CW, Kim KS et al
,
Role of skin prick test and serological measurement of specific IgE in the diagnosis of occupational asthma resulting from exposure to vinyl sulphone reactive dyes
,
Occup Environ Med
,
2001
;
58
:
411-416