Reference

El-Zein M, Malo J-L, Infante-Rivard C, Gautrin D, Incidence of probable occupational asthma and changes in airway calibre and responsiveness in apprentice welders, Eur Respir J, 2003;22:513-519,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Study aimed to determine the incidence of probable occupational asthma (OA), bronchial obstruction and hyper-responsiveness among 286 student welders. Non-specific bronchial reactivity was measurable in 194/204 individuals who were present. There were also individuals who developed non-specific bronchial reactivity without symptoms. Going from a 3.2 fold change to a 2-fold change did not enhance the sensitivity of looking for changes in reactivity. There were also individuals who lost their reactivity (3.1%) about half as often as those who became reactive (6.7%).

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

Paired measurements of non-specific reactivity may be achieved in the workplace.

Non Bohrf Information

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