BOHRF Original Authors' Main Conclusions
The original authors' main conclusions are taken from Abstract, Results and
Discussion. They are decided upon by the authors of the BOHRF occupational
asthma guidelines and form part of the guidelines.
Diurnal variation (DV) in peak expiratory flow rate (PEFR) was studied among 132 workers who accomplished 3 daily PEFR measurements for 3 weeks. DV was calculated as difference between highest and lowest PEFR as percentage of the mean PEFR on each day. Median for the whole group was 5.9%. DV was higher among smokers and workers with work-related pulmonary symptoms. Analysis of variance showed that only age and smoking had a significant effect on DV. 12 workers had abnormally high DV, of whom 7 showed no signs of obstructive respiratory disease by spirometry. If only a single spirometric test had been performed the tentative diagnosis of bronchial asthma could have been missed in these 7 workers.
BOHRF Associated Evidence Statements
The BOHRF occupational asthma guidelines state that this reference is associated
with the following evidence statements
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